SCHEMBL7060105

SCHEMBL7060105

CCCc1ccc(C)c2c1CC=C2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9169221 0.88 TYR (0.38)
SCHEMBL6913096 0.87 HTR2C (0.33) HTR2CHTR2B
SCHEMBL8962157 0.87 TYR (0.41) HTR2C
SCHEMBL8962330 0.87 TYR (0.41) HTR2C
SCHEMBL6911964 0.86
SCHEMBL6914832 0.85
SCHEMBL9171565 0.84 PRKCI (0.32) HTR2CHTR2B
SCHEMBL2973498 0.81 HTR2C (0.30) HTR2CHTR2B
SCHEMBL8962145 0.80 PTGS1 (0.33)
SCHEMBL29495007 0.76 CYP1A2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0969010-B1 Transition metal compound and catalyst containing the same for polymerization of olefins JAPAN POLYOLEFINS CO LTD (JP) 2004-09-22 EP disclosed
US-6352953-B1 TRANSITION METAL COMPLEX HAVING 5-MEMBERED RING FORMED BY TRANSITION METAL COMPOUND OF GROUP IVB, TWO CARBONS, METAL OF GROUP IIIA AND HYDROGEN JAPAN POLYOLEFINS CO., LTD. (JP) 2002-03-05 US disclosed
US-6150544-A Transition metal compound and catalyst containing the same for polymerization of olefins JAPAN POLYOLEFINS CO., LTD. (JP) 2000-11-21 US disclosed
EP-0969010-A2 Transition metal compound and catalyst containing the same for polymerization of olefins Japan Polyolefins Co., Ltd. (JP) 2000-01-05 EP disclosed
EP-0500005-B1 Process for the preparation of substituted indenes HOECHST AG (DE) 1996-02-07 EP disclosed
US-5420320-A Method for preparing cyclopentadienyl-type ligands and metallocene compounds PHILLIPS PETROLEUM COMPANY (US) 1995-05-30 US disclosed
US-5194619-A PROCESS FOR THE PREPARATION OF SUBSTITUTED INDENES HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-16 US disclosed
EP-0500005-A1 Process for the preparation of substituted indenes HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-26 EP disclosed