SCHEMBL7061047

SCHEMBL7061047

CC(C)OC(=O)OC(C)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
HCAR2 Q8TDS4 1/20 0.33
CA12 O43570 3/20 0.30
CA1 P00915 3/20 0.30
CA2 P00918 3/20 0.30
CA7 P43166 3/20 0.30
CA9 Q16790 3/20 0.30
CA14 Q9ULX7 3/20 0.30
LMNA P02545 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8006073 0.92 TSHR (0.35) TSHR
SCHEMBL36670 0.81 TSHR (0.59) TSHRHCAR2CA12CA1CA2
Water SCHEMBL27755453 0.78 TSHR (0.56) TSHRHCAR2CA12CA1CA2
SCHEMBL6729295 0.78 TSHR (0.56) TSHRHCAR2CA12CA1CA2
Ammonia Solution, Strong SCHEMBL16191762 0.78 TSHR (0.56) TSHRHCAR2CA12CA1CA2
SCHEMBL6726188 0.78 TSHR (0.56) TSHRHCAR2CA12CA1CA2
Hydrochloric Acid SCHEMBL15092480 0.78 TSHR (0.56) TSHRHCAR2CA12CA1CA2
Hydrogen Peroxide SCHEMBL28342534 0.78 TSHR (0.56) TSHRHCAR2CA12CA1CA2
Ethylene SCHEMBL10595082 0.75 TSHR (0.53) TSHRHCAR2CA12CA1CA2
Bicarbonate SCHEMBL6046311 0.75 TSHR (0.53) TSHRHCAR2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830336-B1 PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS CROMPTON CORP (US) 2003-05-21 EP disclosed
EP-0830336-A4 PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS OSI SPECIALTIES INC (US) 2000-04-05 EP disclosed
EP-0830336-A1 PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS OSi Specialties, Inc. (US) 1998-03-25 EP disclosed
WO-1996040613-A1 PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS OSI SPECIALTIES, INC. (US) 1996-12-19 WO disclosed
US-5563288-A REACTING DIMETHYL CARBONATE WITH ALCOHOL TO FORM METHYL ALKYL CARBONATE, REACTING CARBONATE WITH TERTIARY ALKANOLAMINE OSI SPECIALTIES, INC. (US) 1996-10-08 US disclosed