Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640292 | 1.00 | MAPT (0.44) | MAPTTSHRBACE1TDP1ALDH1A1 | |
| SCHEMBL9402183 | 1.00 | MAPT (0.44) | MAPTTSHRBACE1TDP1ALDH1A1 | |
| SCHEMBL9402140 | 0.98 | MAPT (0.41) | MAPTTSHRBACE1TDP1ALDH1A1 | |
| SCHEMBL7539674 | 0.89 | TSHR (0.42) | MAPTTSHRBACE1TDP1ALDH1A1 | |
| SCHEMBL2755248 | 0.81 | TSHR (0.37) | MAPTTSHRBACE1TDP1 | |
| SCHEMBL3168007 | 0.79 | TSHR (0.35) | TSHRBACE1TDP1 | |
| SCHEMBL11021416 | 0.79 | TSHR (0.32) | MAPTTSHRBACE1RGS12 | |
| SCHEMBL24001183 | 0.76 | TSHR (0.38) | TSHRBACE1TDP1 | |
| SCHEMBL14354358 | 0.75 | TSHR (0.52) | MAPTTSHRBACE1TDP1ALDH1A1 | |
| SCHEMBL13163013 | 0.75 | PLG (0.37) | TSHRBACE1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338859-A | Reacting a hydantoin with a calcium base; crystallization; precipitation; separation | HOECHST CELANESE CORPORATION (US) | 1994-08-16 | — | — | US | claimed |
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | claimed |
| US-4082767-A | CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-04 | — | — | US | claimed |
| US-20230259028-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING REACTION PRODUCT OF HYDANTOIN COMPOUNDS | NISSAN CHEMICAL CORPORATION (JP) | 2023-08-17 | — | — | US | disclosed |
| US-20230259028-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING REACTION PRODUCT OF HYDANTOIN COMPOUNDS | NISSAN CHEMICAL CORPORATION (JP) | 2023-08-17 | — | — | US | disclosed |
| EP-0989122-B1 | Process for the preparation of imidazolidine-2,4-diones | DEGUSSA (DE) | 2003-05-21 | — | — | EP | disclosed |
| US-6235910-B1 | BY REACTING AN ALDEHYDE COMPOUND WITH A UREA COMPOUND IN THE PRESENCE OF CARBON MONOXIDE AND A CATALYTICALLY ACTIVE METAL COMPOUND. | DEGUSSA-HULS AG (DE) | 2001-05-22 | — | — | US | disclosed |
| JP-2000095765-A | PRODUCTION OF IMIDAZOLIDINE-2,4-DIONE AND ITS USE | DEGUSSA HUELS AG | 2000-04-04 | — | — | JP | disclosed |
| EP-0989122-A1 | Process for the preparation of imidazolidine-2,4-diones | Degussa-Hüls Aktiengesellschaft (DE) | 2000-03-29 | — | — | EP | disclosed |
| US-5338859-A | Reacting a hydantoin with a calcium base; crystallization; precipitation; separation | HOECHST CELANESE CORPORATION (US) | 1994-08-16 | — | — | US | disclosed |
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | disclosed |
| US-4082767-A | CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-04 | — | — | US | disclosed |