Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28333231 | 0.77 | CA12 (0.56) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL2142266 | 0.77 | CA12 (0.56) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL4070257 | 0.77 | CA1 (0.44) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL887989 | 0.74 | EPHX1 (0.46) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL16297135 | 0.74 | EPHX1 (0.46) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL18823066 | 0.74 | EPHX1 (0.46) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL18822970 | 0.74 | EPHX1 (0.46) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL22480 | 0.74 | EPHX1 (0.46) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL1052594 | 0.74 | EPHX1 (0.46) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL28878275 | 0.74 | EPHX1 (0.46) | CA12CA1CA2CA9EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153704-A1 | Polymer-coated metal composites by dip autopolymerization | BELL JAMES P (US) | 2003-08-14 | — | — | US | disclosed |
| US-6555239-B1 | Dipping the metal substrate in an acidic solution of 4-carboxyphenyl maleimide, and n-phenyl maleimide, 2-(methacryloyloxy)ethyl acetoacetate, methyl methacrylate or acrylonitrile for a time in the absence of other catalysts | THE UNIVERSITY OF CONNECTICUT | 2003-04-29 | — | — | US | disclosed |
| US-6451383-B2 | APPLYING AN ACIDIC STARTING SOLUTION OF AN EMULSION OF CHEMICALLY DISTINCT MONOMERS TO A METAL SUBSTRATE WHICH CAN INITIATE POLYMERIZATION | THE UNIVERSITY OF CONNECTICUT | 2002-09-17 | — | — | US | disclosed |
| US-6355354-B1 | FOR CORROSION AND EROSION RESISTANCE, ABRASION RESISTANCE, AND ELECTRICAL AND THERMAL INSULATION | THE UNIVERSITY OF CONNECTICUT | 2002-03-12 | — | — | US | disclosed |
| US-20010051223-A1 | Polymer-coated metal composites by dip autopolymerization | BELL JAMES P (US) | 2001-12-13 | — | — | US | disclosed |
| EP-1154866-A1 | POLYMER-COATED METAL COMPOSITES BY DIP AUTOPOLYMERIZATION | The University of Connecticut (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0917495-A4 | COMPOSITION AND METHOD FOR COATING METALS BY DIP AUTOPOLYMERIZATION | UNIV CONNECTICUT (US) | 2001-04-25 | — | — | EP | disclosed |
| WO-2000048750-A1 | POLYMER-COATED METAL COMPOSITES BY DIP AUTOPOLYMERIZATION | UNIVERSITY OF CONNECTICUT (US) | 2000-08-24 | — | — | WO | disclosed |
| EP-0917495-A1 | COMPOSITION AND METHOD FOR COATING METALS BY DIP AUTOPOLYMERIZATION | THE UNIVERSITY OF CONNECTICUT (US) | 1999-05-26 | — | — | EP | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5807612-A | FORMING DECORATIVE OR PROTECTIVE OVERCOATING | THE UNIVERSITY OF CONNECTICUT (US) | 1998-09-15 | — | — | US | disclosed |
| WO-1998005436-A1 | COMPOSITION AND METHOD FOR COATING METALS BY DIP AUTOPOLYMERIZATION | THE UNIVERSITY OF CONNECTICUT (US) | 1998-02-12 | — | — | WO | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |