SCHEMBL7062648

SCHEMBL7062648

CCCCCOC[C@H](COC(=O)[C@@H](N)COP(=O)(O)O)OCCCCC

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LPAR3 Q9UBY5 7/20 0.71
▸ LPAR1 Q92633 6/20 0.71
▸ LPAR5 Q9H1C0 1/20 0.53
▸ LPAR2 Q9HBW0 1/20 0.52
▸ S1PR2 O95136 3/20 0.49
▸ S1PR1 P21453 3/20 0.49
▸ S1PR3 Q99500 3/20 0.49
▸ S1PR5 Q9H228 1/20 0.49
▸ ENPP2 Q13822 5/20 0.46
▸ TLR2 O60603 3/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ P2RY10 O00398 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL370759 0.85 LPAR3 (0.97) LPAR3LPAR1LPAR5LPAR2ENPP2
SCHEMBL2732573 0.85 LPAR3 (0.97) LPAR3LPAR1LPAR5LPAR2ENPP2
SCHEMBL5055004 0.83 LPAR3 (1.00) LPAR3LPAR1LPAR5LPAR2ENPP2
SCHEMBL2814732 0.83 LPAR3 (1.00) LPAR3LPAR1LPAR5LPAR2ENPP2
SCHEMBL31198159 0.83 LPAR3 (1.00) LPAR3LPAR1LPAR5LPAR2ENPP2
SCHEMBL2813163 0.83 LPAR3 (1.00) LPAR3LPAR1LPAR5LPAR2ENPP2
SCHEMBL496845 0.83 LPAR3 (1.00) LPAR3LPAR1LPAR5LPAR2ENPP2
SCHEMBL31439420 0.83 LPAR3 (1.00) LPAR3LPAR1LPAR5LPAR2ENPP2
SCHEMBL10896195 0.83 LPAR3 (1.00) LPAR3LPAR1LPAR5LPAR2ENPP2
SCHEMBL29458233 0.83 LPAR3 (1.00) LPAR3LPAR1LPAR5LPAR2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0119056-B1 SURFACTANT COMPOSITION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME FOR USE IN THE TREATMENT OF RESPIRATORY DISTRESS SYNDROME TOKYO TANABE COMPANY LIMITED (JP) 1990-08-29 — — EP claimed
US-4603124-A FILM-FORMING MIXTURE OF CHOLINE PHOSPHO GLYCERIDE, ACID PHOSPHOLIPID, FATTY ACID, AND LIPOPROTEIN TOKYO TANABE COMPANY, LIMITED (JP) 1986-07-29 — — US claimed
EP-0119056-A2 Surfactant composition and pharmaceutical compositions containing same for use in the treatment of respiratory distress syndrome TOKYO TANABE COMPANY LIMITED (JP) 1984-09-19 — — EP claimed
EP-0935139-B1 IMMUNOHISTOCHEMICAL STAINING COMPOSITION DAIICHI PURE CHEMICALS CO LTD (JP) 2004-11-17 — — EP disclosed
EP-0733645-B1 NOVEL SYNTHETIC PEPTIDE, LUNG SURFACTANT CONTAINING THE SAME, AND REMEDY FOR RESPIRATORY DISTRESS SYNDROME MITSUBISHI PHARMA CORP (JP) 2003-03-19 — — EP disclosed
US-20020028474-A1 Composition for immunohistochemical staining DAIICHI PURE CHEMICAL CO., LTD. (JP) 2002-03-07 — — US disclosed
US-6042622-A Process for crystallization of alkali metal bicarbonate salts BASF CORPORATION (US) 2000-03-28 — — US disclosed
EP-0935139-A1 IMMUNOHISTOCHEMICAL STAINING COMPOSITION DAIICHI PURE CHEMICALS CO., LTD. (JP) 1999-08-11 — — EP disclosed
US-5827825-A POLYPEPTIDE FROM THE CONDENSATION OF VARIABLE HEXA- OR HEPTAPEPTIDES WITH PEPTIDES CONTAINING TWELVE TO TWENTY UNITS OF LEUCINE AND/OR NORLEUCINE, FOR TREATMENT OF RESPIRATORY DISORDERS TOKYO TANABE COMPANY LTD. (JP) 1998-10-27 — — US disclosed
US-5716419-A Process for crystallization of mineral salts PPG INDUSTRIES, INC. (US) 1998-02-10 — — US disclosed
EP-0733645-A1 NOVEL SYNTHETIC PEPTIDE, LUNG SURFACTANT CONTAINING THE SAME, AND REMEDY FOR RESPIRATORY DISTRESS SYNDROME TOKYO TANABE COMPANY LIMITED (JP) 1996-09-25 — — EP disclosed
EP-0652011-A1 PROPHYLACTIC AND REMEDY FOR VIRAL DISEASES IN RESPIRATORY TRACT TOKYO TANABE COMPANY LIMITED (JP) 1995-05-10 — — EP disclosed
EP-0119056-B1 SURFACTANT COMPOSITION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME FOR USE IN THE TREATMENT OF RESPIRATORY DISTRESS SYNDROME TOKYO TANABE COMPANY LIMITED (JP) 1990-08-29 — — EP disclosed
US-4603124-A FILM-FORMING MIXTURE OF CHOLINE PHOSPHO GLYCERIDE, ACID PHOSPHOLIPID, FATTY ACID, AND LIPOPROTEIN TOKYO TANABE COMPANY, LIMITED (JP) 1986-07-29 — — US disclosed
EP-0119056-A2 Surfactant composition and pharmaceutical compositions containing same for use in the treatment of respiratory distress syndrome TOKYO TANABE COMPANY LIMITED (JP) 1984-09-19 — — EP disclosed
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