SCHEMBL7063205

SCHEMBL7063205

C=C(C)C(N)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL27848779 0.78
SCHEMBL8279795 0.73
SCHEMBL8584045 0.73
SCHEMBL744385 0.73
SCHEMBL3201145 0.73
SCHEMBL11049637 0.72 TDP1 (0.39)
SCHEMBL19041753 0.72
Thioacetamide SCHEMBL5998997 0.71 TSHR (0.56)
SCHEMBL24739 0.71
Thioacetamide SCHEMBL5998967 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383905-A1 FGFR INHIBITORS AND METHODS OF USE THEREOF 3H PHARMACEUTICALS CO., LTD. (CN) 2024-11-21 US disclosed
WO-2012087237-A1 COMPOUNDS AND THEIR USE AS BACE INHIBITORS ASTRAZENECA AB (SE) 2012-06-28 WO disclosed
US-20030153704-A1 Polymer-coated metal composites by dip autopolymerization BELL JAMES P (US) 2003-08-14 US disclosed
US-6555239-B1 Dipping the metal substrate in an acidic solution of 4-carboxyphenyl maleimide, and n-phenyl maleimide, 2-(methacryloyloxy)ethyl acetoacetate, methyl methacrylate or acrylonitrile for a time in the absence of other catalysts THE UNIVERSITY OF CONNECTICUT 2003-04-29 US disclosed
US-6451383-B2 APPLYING AN ACIDIC STARTING SOLUTION OF AN EMULSION OF CHEMICALLY DISTINCT MONOMERS TO A METAL SUBSTRATE WHICH CAN INITIATE POLYMERIZATION THE UNIVERSITY OF CONNECTICUT 2002-09-17 US disclosed
US-6355354-B1 FOR CORROSION AND EROSION RESISTANCE, ABRASION RESISTANCE, AND ELECTRICAL AND THERMAL INSULATION THE UNIVERSITY OF CONNECTICUT 2002-03-12 US disclosed
US-20010051223-A1 Polymer-coated metal composites by dip autopolymerization BELL JAMES P (US) 2001-12-13 US disclosed
EP-1154866-A1 POLYMER-COATED METAL COMPOSITES BY DIP AUTOPOLYMERIZATION The University of Connecticut (US) 2001-11-21 EP disclosed
EP-0917495-A4 COMPOSITION AND METHOD FOR COATING METALS BY DIP AUTOPOLYMERIZATION UNIV CONNECTICUT (US) 2001-04-25 EP disclosed
EP-0787157-B1 OLEAGINOUS COMPOSITIONS COMPRISING GRAFTED ISOMONOOLEFIN ALKYLSTYRENE POLYMERS INFINEUM USA LP (US) 2000-12-20 EP disclosed
EP-0369641-A1 Improved dispersant additives prepared from monoepoxy thiols EXXON CHEMICAL PATENTS INC. (US) 1990-05-23 EP disclosed
EP-0368548-A1 Improved amide dispersant additives derived from amido-amines EXXON CHEMICAL PATENTS INC. (US) 1990-05-16 EP disclosed
WO-1990004625-A2 AMIDE CONTAINING FRICTION MODIFIER FOR USE IN POWER TRANSMISSION FLUIDS EXXON CHEMICAL COMPANY (US) 1990-05-03 WO disclosed
EP-0357217-A2 Ethylene alpha-olefin copolymer substituted amino phenol mannich base lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-03-07 EP disclosed
US-4906659-A Antibiotic tan-749, its derivatives, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-03-06 US disclosed
EP-0356010-A1 Ethylene alpha-olefin polymer substituted Mannich base lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-02-28 EP disclosed
EP-0353935-A1 Ethylene alpha-olefin polymer substituted mono-and dicarboxylic acid lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-02-07 EP disclosed
EP-0336664-A2 Improved dispersant additives derived from amido-amine adducts EXXON CHEMICAL PATENTS INC. (US) 1989-10-11 EP disclosed
US-4857217-A ADDUCT OF POLYOLEFIN MODIFIED WITH AN ACID AND POLYAMINE MODIFIED WITH (THIO)AMIDO COMPOUND EXXON CHEMICAL PATENTS INC. (US) 1989-08-15 US disclosed
EP-0319229-A2 Improved dispersant additives derived from amido-amines EXXON CHEMICAL PATENTS INC. (US) 1989-06-07 EP disclosed