Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.66 |
| ▸ | BACE2 | Q9Y5Z0 | 5/20 | 0.66 |
| ▸ | CTSD | P07339 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376142 | 1.00 | BACE1 (0.66) | BACE1BACE2CTSD | |
| SCHEMBL6807520 | 1.00 | BACE1 (0.66) | BACE1BACE2CTSD | |
| SCHEMBL5376143 | 1.00 | BACE1 (0.66) | BACE1BACE2CTSD | |
| SCHEMBL5367912 | 0.90 | BACE1 (0.65) | BACE1BACE2CTSD | |
| SCHEMBL5367907 | 0.90 | BACE1 (0.65) | BACE1BACE2CTSD | |
| SCHEMBL5374149 | 0.90 | BACE1 (0.65) | BACE1BACE2CTSD | |
| SCHEMBL5372551 | 0.90 | BACE1 (0.64) | BACE1BACE2CTSD | |
| SCHEMBL5375434 | 0.90 | BACE1 (0.64) | BACE1BACE2CTSD | |
| SCHEMBL5365694 | 0.89 | BACE1 (0.65) | BACE1BACE2CTSD | |
| SCHEMBL6802169 | 0.89 | BACE1 (0.65) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058686-A1 | HYDROXYPROPYL AMIDES FOR THE TREATMENT OF ALZHEIMER’S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | claimed |