Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.62 |
| ▸ | PPARG | P37231 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
| ▸ | PPARD | Q03181 | 2/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | FABP4 | P15090 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706354 | 1.00 | CNR1 (0.62) | CNR1PPARGFFAR1PPARDPPARA | |
| SCHEMBL29379789 | 1.00 | CNR1 (0.62) | CNR1PPARGFFAR1PPARDPPARA | |
| SCHEMBL29484564 | 1.00 | CNR1 (0.62) | CNR1PPARGFFAR1PPARDPPARA | |
| Fluoride SCHEMBL27714586 | 0.98 | CNR1 (0.61) | CNR1PPARGFFAR1PPARDPPARA | |
| SCHEMBL1370453 | 0.93 | PPARG (0.59) | CNR1PPARGFFAR1PPARDPPARA | |
| SCHEMBL10481473 | 0.93 | PPARG (0.59) | CNR1PPARGFFAR1PPARDPPARA | |
| SCHEMBL10481472 | 0.93 | PPARG (0.59) | CNR1PPARGFFAR1PPARDPPARA | |
| SCHEMBL8402956 | 0.93 | PPARG (0.59) | CNR1PPARGFFAR1PPARDPPARA | |
| SCHEMBL17583505 | 0.93 | ACE2 (0.59) | CNR1PPARGPPARDPPARAUSP2 | |
| SCHEMBL6437153 | 0.93 | ACE2 (0.59) | CNR1PPARGPPARDPPARAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116585306-A | PLA2 inhibitors for immediate treatment of hymenoptera toxicity and other conditions due to histamine release | 奥菲瑞克斯股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-109562098-B | PLA2 inhibitors for immediate treatment of hymenoptera toxicity and other conditions due to histamine release | 奥菲瑞克斯股份有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-107249578-B | Method for treating envenomation and related pharmaceutical composition, system and kit | 奥菲瑞克斯股份有限公司 | 2021-01-26 | — | — | CN | disclosed |
| US-10351871-B2 | Desaturases and methods of using them for synthesis of polyunsaturated fatty acids | WASHINGTON STATE UNIVERSITY (US) | 2019-07-16 | — | — | US | disclosed |
| CN-109562098-A | PLA2 and HMG-COA inhibitors for the treatment of pathological conditions causing haemolysis, cerebrovascular and acute renal injury | 奥菲瑞克斯股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| US-20180346944-A1 | METHOD OF PRODUCING POLYUNSATURATED FATTY ACID | CITY UNIVERSITY OF HONG KONG (HK) | 2018-12-06 | — | — | US | disclosed |
| CN-107249578-A | Venom is stung into treatment method and relevant pharmaceutical composition, system and kit | 奥菲瑞克斯股份有限公司 | 2017-10-13 | — | — | CN | disclosed |
| US-20170283839-A1 | DESATURASES AND METHODS OF USING THEM FOR SYNTHESIS OF POLYUNSATURATED FATTY ACIDS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION | 2017-10-05 | — | — | US | disclosed |
| US-9695450-B2 | Desaturases and methods of using them for synthesis of polyunsaturated fatty acids | WASHINGTON STATE UNIVERSITY (US) | 2017-07-04 | — | — | US | disclosed |
| US-20140298502-A1 | DESATURASES AND METHODS OF USING THEM FOR SYNTHESIS OF POLYUNSATURATED FATTY ACIDS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-10-02 | — | — | US | disclosed |
| US-7402735-B2 | Desaturases and methods of using them for synthesis of polyunsaturated fatty acids | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-07-22 | — | — | US | disclosed |
| EP-1147174-B1 | DESATURASES AND METHODS OF USING THEM FOR SYNTHESIS OF POLYUNSATURATED FATTY ACIDS | UNIV WASHINGTON (US) | 2007-02-14 | — | — | EP | disclosed |
| US-20060090221-A1 | Desaturases and methods of using them for synthesis of polyunsaturated fatty acids | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION | 2006-04-27 | — | — | US | disclosed |
| US-6825017-B1 | FOR DIETETICS; COMPRISES VECTORS WHICH TRANSFORM PLANTS/YEASTS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION | 2004-11-30 | — | — | US | disclosed |
| EP-1147174-A4 | DESATURASES AND METHODS OF USING THEM FOR SYNTHESIS OF POLYUNSATURATED FATTY ACIDS | UNIV WASHINGTON (US) | 2004-10-06 | — | — | EP | disclosed |
| US-20030152983-A1 | Dna sequences; fatty acid | UNIVERSITY OF BRISTOL (GB) | 2003-08-14 | — | — | US | disclosed |
| EP-1147174-A1 | DESATURASES AND METHODS OF USING THEM FOR SYNTHESIS OF POLYUNSATURATED FATTY ACIDS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2001-10-24 | — | — | EP | disclosed |
| EP-1042485-A2 | DESATURASE | UNIVERSITY OF BRISTOL (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-2000034439-A1 | DESATURASES AND METHODS OF USING THEM FOR SYNTHESIS OF POLYUNSATURATED FATTY ACIDS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-1999033958-A2 | DESATURASE | UNIVERSITY OF BRISTOL (GB) | 1999-07-08 | — | — | WO | disclosed |