Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 8/20 | 0.54 |
| ▸ | MMP2 | P08253 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27802281 | 0.84 | KDM4E (0.65) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL27780771 | 0.83 | KDM4E (0.64) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL3560424 | 0.82 | KDM4E (0.68) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL829242 | 0.81 | KDM4E (0.76) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7447241 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10395119 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5843089 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28004667 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5842347 | 0.80 | KDM4E (0.65) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13174359 | 0.79 | KDM4E (0.72) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212113-A1 | Novel aromatic compounds and poly(oxyalkylene) containing aromatic compounds possessing antibacterial, antifungal or antitumor activity | GLAXOSMITHKLINE LLC | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212113-A1 | Novel aromatic compounds and poly(oxyalkylene) containing aromatic compounds possessing antibacterial, antifungal or antitumor activity | TYR, CYP51A1, ODC1 | KDM4E 1515/4885ALDH1A1 597/4885HPGD 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.