SCHEMBL7063635

SCHEMBL7063635

N#CC(=CC1([SiH3])CCCCO1)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3459542 0.77
SCHEMBL28539611 0.73
SCHEMBL4628092 0.70
Oxalic Acid SCHEMBL29011315 0.70
SCHEMBL5175008 0.67
SCHEMBL4885771 0.67
SCHEMBL7060146 0.66
SCHEMBL27777659 0.65
SCHEMBL9148473 0.65
SCHEMBL14676199 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6607631-B1 Polymerizable monomer adhesive composition includes a 1,1-disubstituted ethylene monomer and at least one slip additive, where the slip additive causes a polymer film formed from the monomer to have a lower coefficient of friction than in an CLOSURE MEDICAL CORPORATION 2003-08-19 US disclosed
US-6488944-B2 APPLYING A MIXTURE COMPRISING POLYMERIZABLE 1,1-DISUBSTITUTED ETHYLENE ADHESIVE MONOMER AND POLYDIMETHYLSILOXANE, A SILOXANE MONOMER OR POLYMER, A FLUORINATED SILOXANE, AND A SILOXANE ON AN AREA OF TISSUE WHERE SCAR TISSUE IS PRESENT CLOSURE MEDICAL CORPORATION 2002-12-03 US disclosed
EP-1240265-A2 1,1-DISUBSTITUTED ETHYLENE ADHESIVE COMPOSITIONS CONTAINING POLYDIMETHYLSILOXANE Closure Medical Corporation (US) 2002-09-18 EP disclosed
WO-2002020684-A2 ADHESIVE COMPOSITIONS WITH REDUCED COEFFICIENT OF FRICTION CLOSURE MEDICAL CORPORATION (US) 2002-03-14 WO disclosed
US-20020012678-A1 1, 1-disubstituted ethylene adhesive compositions containing polydimethysiloxane CLOSURE MEDICAL CORPORATION 2002-01-31 US disclosed
WO-2001046327-A2 1,1-DISUBSTITUTED ETHYLENE ADHESIVE COMPOSITIONS CONTAINING POLYDIMETHYLSILOXANE CLOSURE MEDICAL CORPORATION (US) 2001-06-28 WO disclosed