SCHEMBL7064398

SCHEMBL7064398

C=CCCCCOCC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7067316 0.98 LPAR3 (0.32) LPAR3LPAR2
SCHEMBL7067386 0.90 LPAR3 (0.31) LPAR3LPAR2
SCHEMBL7063589 0.88
SCHEMBL15524095 0.86 LPAR3 (0.35) LPAR3LPAR2
SCHEMBL15603495 0.86 LPAR3 (0.35) LPAR3LPAR2
SCHEMBL7066122 0.86
SCHEMBL8020064 0.85
SCHEMBL15524643 0.84 MEN1 (0.37) LPAR3LPAR2
SCHEMBL15524011 0.84 MEN1 (0.37) LPAR3LPAR2
SCHEMBL7064654 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1042302-B1 LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION MINNESOTA MINING & MFG (US) 2003-09-24 EP disclosed
EP-0973844-B1 COMPOUNDS AND PROCESS FOR CONTROLLING CONE TILT ANGLE IN MIXTURES OF SMECTIC LIQUID CRYSTAL COMPOUNDS MINNESOTA MINING & MFG (US) 2003-06-04 EP disclosed
US-6309561-B1 Liquid crystal compounds having a chiral fluorinated terminal portion 3M INNOVATIVE PROPERTIES COMPANY 2001-10-30 US disclosed
EP-1042302-A1 LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-10-11 EP disclosed
EP-0973844-A1 COMPOUNDS AND PROCESS FOR CONTROLLING CONE TILT ANGLE IN MIXTURES OF SMECTIC LIQUID CRYSTAL COMPOUNDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-01-26 EP disclosed
WO-1999033814-A1 LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-07-08 WO disclosed
US-5855812-A ALIPHATIC FLUOROCARBON TERMINAL PORTION COMPRISING A TERMINAL FLUOROALKYL OR FLUOROETHER GROUP AND AN ALKYLENE GROUP HAVING AT LEAST TWO CARBON ATOMS AND CONTAINING AT LEAST ONE CATENARY ETHER OXYGEN ATOM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-01-05 US disclosed
WO-1998046697-A1 COMPOUNDS AND PROCESS FOR CONTROLLING CONE TILT ANGLE IN MIXTURES OF SMECTIC LIQUID CRYSTAL COMPOUNDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-22 WO disclosed