Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.51 |
| ▸ | PTPRA | P18433 | 3/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064440 | 1.00 | PTPN1 (0.54) | PTPN1PTPN2PTPRAMYCMAX | |
| SCHEMBL7204760 | 1.00 | PTPN1 (0.54) | PTPN1PTPN2PTPRAMYCMAX | |
| SCHEMBL7571001 | 0.84 | PTPN1 (0.71) | PTPN1PTPN2PTPRAMYCMAX | |
| SCHEMBL7576946 | 0.84 | PTPN1 (0.71) | PTPN1PTPN2PTPRAMYCMAX | |
| SCHEMBL7570995 | 0.84 | PTPN1 (0.71) | PTPN1PTPN2PTPRAMYCMAX | |
| SCHEMBL7204762 | 0.79 | PTPN1 (0.57) | PTPN1PTPN2PTPRA | |
| SCHEMBL7064445 | 0.79 | PTPN1 (0.57) | PTPN1PTPN2PTPRA | |
| SCHEMBL7065601 | 0.70 | PTPN1 (1.00) | PTPN1PTPN2PTPRA | |
| SCHEMBL7568932 | 0.70 | PTPN1 (1.00) | PTPN1PTPN2PTPRA | |
| SCHEMBL7065596 | 0.70 | PTPN1 (1.00) | PTPN1PTPN2PTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313696-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018323-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |