2-Phenylthiazole

2-Phenylthiazole

SCHEMBL70646

c1ccc(-c2nccs2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 1.00
CYP2A6 P11509 1/20 0.64
LOXL2 Q9Y4K0 1/20 0.59
ADRB2 P07550 1/20 0.53
PTGDR2 Q9Y5Y4 1/20 0.49
KDR P35968 1/20 0.49
RAB9A P51151 2/20 0.48
HDAC2 Q92769 2/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
KAT6A Q92794 1/20 0.44
GRM5 P41594 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylthiazole SCHEMBL10667585 0.98 PDPK1 (0.95) PDPK1CYP2A6LOXL2ADRB2PTGDR2
2-Phenylthiazole SCHEMBL4939218 0.98 PDPK1 (0.95) PDPK1CYP2A6LOXL2ADRB2PTGDR2
2-Phenylthiazole SCHEMBL28319382 0.98 PDPK1 (0.95) PDPK1CYP2A6LOXL2ADRB2PTGDR2
2-Phenylthiazole SCHEMBL10519953 0.98 PDPK1 (0.95) PDPK1CYP2A6LOXL2ADRB2PTGDR2
2-Phenylthiazole SCHEMBL27882225 0.98 PDPK1 (0.95) PDPK1CYP2A6LOXL2ADRB2PTGDR2
SCHEMBL5147639 0.96 PDPK1 (0.91) PDPK1CYP2A6LOXL2ADRB2PTGDR2
2-Phenylthiazole SCHEMBL3034058 0.94 PDPK1 (0.88) PDPK1CYP2A6LOXL2ADRB2PTGDR2
2-Phenylthiazole SCHEMBL27932141 0.92 PDPK1 (0.84) PDPK1CYP2A6LOXL2ADRB2PTGDR2
2-Phenylthiazole SCHEMBL28287735 0.88 PDPK1 (0.78) PDPK1CYP2A6LOXL2ADRB2PTGDR2
2-Phenylthiazole SCHEMBL28126546 0.88 PDPK1 (0.78) PDPK1CYP2A6LOXL2ADRB2PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2221 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260117393-A1 ETCHING AGENT COMPOSITION AND ETCHING METHOD USING THE SAME KCTECH CO., LTD. (KR) 2026-04-30 US claimed
CN-120166857-A Photoelectric device, preparation method thereof and display device TCL科技集团股份有限公司 2025-06-17 CN claimed
CN-120058694-A Phenyl thiazole isoxazoline/isoxazole compound and application thereof as agricultural bactericide 湖北科技学院 2025-05-30 CN claimed
CN-120025331-A Pyrazole hydrazide derivative containing phenylthiazole fragment and application thereof 安徽理工大学 2025-05-23 CN claimed
CN-119431355-A Phenyl thiazole derivative, composition and application thereof 徐州医科大学 2025-02-14 CN claimed
CN-118994141-A Phenylthiazole derivative with anti-liver cancer and anti-inflammatory activities and preparation method and application thereof 河南科技大学 2024-11-22 CN claimed
US-11987588-B2 Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2024-05-21 US claimed
CN-118027085-A Organic electroluminescent compound and application thereof 宁波卢米蓝新材料有限公司 2024-05-14 CN claimed
CN-117903168-A Pyrrolo [2,3-d ] thiazole derivatives, and preparation method and application thereof 南开大学 2024-04-19 CN claimed
CN-117209488-A Alkaloid barakacin derivative, synthesis thereof and application thereof in prevention and treatment of plant virus and germ diseases 天津师范大学 2023-12-12 CN claimed
EP-0283036-A1 Benzoxazine derivatives and processes for preparation thereof TANABE SEIYAKU CO., LTD. (JP) 1988-09-21 EP claimed
US-4762921-A 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives PFIZER INC. (US) 1988-08-09 US claimed
US-4675186-A 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives PFIZER INC. (US) 1987-06-23 US claimed
EP-0201221-A1 6-(1-acyl-1-hydroxy methyl) penicillanic acid derivatives PFIZER INC. (US) 1986-11-12 EP claimed
EP-0139183-A2 Herbicidal agents containing a photosynthesis inhibitor herbicide together with substituted azolyl derivatives BAYER AG (DE) 1985-05-02 EP claimed
EP-0139182-A2 Herbicidal agents containing a photosynthesis inhibitor herbicide together with 1,4-disubstituted pyrazole derivatives BAYER AG (DE) 1985-05-02 EP claimed
EP-0139227-A2 Herbicidal agents containing a photosynthesis inhibitor herbicide together with azolylmethyl ketones BAYER AG (DE) 1985-05-02 EP claimed
EP-0138002-A2 Herbicidal agents containing a photosynthesis inhibitor herbicide together with pyridincarboxylic-acid amides BAYER AG (DE) 1985-04-24 EP claimed
US-4336377-A Basic dioxazine compounds CIBA-GEIGY CORPORATION (US) 1982-06-22 US claimed
EP-0029934-A1 Benzopyrano derivatives, pharmaceutical compositions containing them and processes for preparing the compounds and compositions SCHERING CORPORATION (US) 1981-06-10 EP claimed