Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.39 |
| ▸ | PTPRF | P10586 | 2/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062879 | 0.92 | PTPN1 (0.46) | PTPN1PTPN2PTPRFPTPRAKEAP1 | |
| SCHEMBL7065292 | 0.90 | PTPN1 (0.54) | PTPN1PTPN2PTPRFPTPRAKEAP1 | |
| SCHEMBL7065578 | 0.89 | PTPN1 (0.47) | PTPN1PTPN2PTPRFPTPRAKEAP1 | |
| SCHEMBL7065207 | 0.89 | PTPN1 (0.47) | PTPN1PTPN2PTPRFPTPRAKEAP1 | |
| SCHEMBL7065977 | 0.87 | PTPN1 (0.44) | PTPN1PTPN2PTPRFPTPRAKEAP1 | |
| SCHEMBL7065299 | 0.87 | PTPN1 (0.45) | PTPN1PTPN2PTPRFPTPRAKEAP1 | |
| SCHEMBL7064357 | 0.85 | PTPN1 (0.46) | PTPN1PTPN2PTPRFPTPRAKEAP1 | |
| SCHEMBL7569472 | 0.84 | PTPN1 (0.44) | PTPN1PTPN2PTPRFPTPRAKEAP1 | |
| SCHEMBL7064535 | 0.84 | PTPN1 (0.48) | PTPN1PTPN2PTPRFPTPRA | |
| SCHEMBL7064405 | 0.83 | PTPN1 (0.57) | PTPN1PTPN2PTPRFPTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313696-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-05-28 | — | — | EP | claimed |
| US-20020035137-A1 | Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBOTT LABORATORIES | 2002-03-21 | — | — | US | claimed |
| WO-2002018323-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | claimed |
| EP-1313696-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-05-28 | — | — | EP | disclosed |
| US-20020035137-A1 | Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBOTT LABORATORIES | 2002-03-21 | — | — | US | disclosed |
| WO-2002018323-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035137-A1 | Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors | PPM1A, PTPRO, PTP4A1 | PTPN1 10/4885PTPN2 29/4885PTPRF 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.