Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226227 | 0.80 | HMGCR (0.49) | HMGCRGAAKMT2ANR1I2MEN1 | |
| SCHEMBL6909440 | 0.78 | HMGCR (0.50) | HMGCRGAAKMT2ANR1I2MEN1 | |
| SCHEMBL27571607 | 0.76 | HMGCR (0.56) | HMGCRGAAKMT2ANR1I2MEN1 | |
| SCHEMBL9222249 | 0.76 | GAA (0.47) | HMGCRGAAKMT2ANR1I2MEN1 | |
| SCHEMBL27570668 | 0.74 | HMGCR (0.59) | HMGCRGAAKMT2ANR1I2MEN1 | |
| SCHEMBL1305322 | 0.73 | HMGCR (0.58) | HMGCRGAAKMT2ANR1I2MEN1 | |
| SCHEMBL27909258 | 0.72 | HMGCR (0.60) | HMGCRGAAKMT2ANR1I2MEN1 | |
| SCHEMBL39364 | 0.71 | HMGCR (0.62) | HMGCRGAAKMT2ANR1I2MEN1 | |
| SCHEMBL1704691 | 0.71 | HMGCR (1.00) | HMGCRGAAKMT2ANR1I2MEN1 | |
| SCHEMBL564169 | 0.70 | HMGCR (0.61) | HMGCRGAAKMT2ANR1I2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019358-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1994-09-01 | — | — | WO | disclosed |