Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22367764 | 0.78 | GRIK1 (0.42) | GRIK1GRIK2 | |
| SCHEMBL18945347 | 0.76 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL8462460 | 0.73 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL18469347 | 0.72 | — | — | |
| SCHEMBL17567261 | 0.72 | RNPEP (0.37) | MMP1MMP3 | |
| SCHEMBL28598156 | 0.69 | TSHR (0.37) | MMP1MMP2MMP3MMP7 | |
| SCHEMBL21248664 | 0.69 | TSHR (0.37) | MMP1MMP2MMP3MMP7 | |
| SCHEMBL11031028 | 0.69 | — | — | |
| SCHEMBL11031026 | 0.69 | — | — | |
| SCHEMBL8459621 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045324-A2 | 14-METHYL-EPOTHILONES | KOSAN BIOSCIENCES, INC. (US) | 2003-06-05 | — | — | WO | disclosed |