Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245099 | 1.00 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL11796568 | 1.00 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL6242823 | 1.00 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL3879583 | 0.98 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL4424531 | 0.96 | TRIM24 (0.46) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL2692193 | 0.93 | TRIM24 (0.43) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL2692046 | 0.91 | TRIM24 (0.43) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL2691711 | 0.87 | TRIM24 (0.40) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL11807268 | 0.87 | TRIM24 (0.40) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL7738607 | 0.87 | TRIM24 (0.40) | TRIM24TRIM33ALDH1A1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313692-A1 | NOVEL MACROCYCLIC KETONES | HAARMANN & REIMER GMBH (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002012157-A1 | NOVEL MACROCYCLIC KETONES | HAARMANN & REIMER GMBH (DE) | 2002-02-14 | — | — | WO | disclosed |