Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10010802 | 0.78 | NPC1 (0.36) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL7064864 | 0.78 | CYP4F2 (0.43) | TSHRCYP1A2 | |
| SCHEMBL27657800 | 0.77 | NPC1 (0.41) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL2478567 | 0.77 | NPC1 (0.41) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL4675815 | 0.77 | NPC1 (0.35) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL4675818 | 0.77 | GAA (0.36) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL10010713 | 0.76 | NPC1 (0.34) | NPC1 | |
| SCHEMBL6521506 | 0.76 | NPC1 (0.34) | NPC1 | |
| SCHEMBL16815032 | 0.75 | NPC1 (0.39) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL4677677 | 0.75 | NPC1 (0.39) | NPC1TSHRCYP1A2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-11-20 | — | — | US | disclosed |
| US-6586368-B1 | Benzofuran derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | CBR3, CBR1, HAAO | NPC1 4434/4885TSHR 1858/4885CYP1A2 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.