Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.67 |
| ▸ | RRM1 | P23921 | 1/20 | 0.61 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.57 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.57 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.53 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700853 | 1.00 | DPP7 (0.67) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL6238460 | 0.98 | DPP7 (0.65) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL30500752 | 0.98 | DPP7 (0.65) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL20707200 | 0.98 | DPP7 (0.65) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL6413585 | 0.98 | DPP7 (0.65) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL30865485 | 0.98 | DPP7 (0.65) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL20801620 | 0.98 | DPP7 (0.65) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL7771240 | 0.96 | DPP7 (0.62) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL7769073 | 0.96 | DPP7 (0.62) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL22987681 | 0.94 | DPP7 (0.58) | DPP7RRM1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313696-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-05-28 | — | — | EP | claimed |
| WO-2002018323-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | claimed |
| US-7803572-B2 | Protease detection assay | ATLAS GENETICS, LTD. (GB) | 2010-09-28 | — | — | US | disclosed |
| EP-1511472-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF ANTHRAX AND INHIBITING LETHAL FACTOR | MERCK & CO INC (US) | 2009-04-29 | — | — | EP | disclosed |
| EP-1313696-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018323-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |