SCHEMBL7066459

SCHEMBL7066459

COc1ccc(C(CN(C)N)OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 17/20 1.00
SLC2A1 P11166 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6744940 0.80 AOC3 (1.00) AOC3
SCHEMBL6742350 0.79 AOC3 (1.00) AOC3SLC2A1
SCHEMBL11483697 0.77 AOC3 (0.62) AOC3SLC2A1CYP1A2CYP2D6CYP2C19
SCHEMBL13569328 0.77 AOC3 (0.62) AOC3SLC2A1CYP1A2CYP2D6CYP2C19
SCHEMBL17666418 0.75 AOC3 (0.59) AOC3SLC2A1CYP1A2CYP2D6CYP2C19
SCHEMBL28371171 0.74 AOC3 (0.59) AOC3CYP1A2CYP2D6CYP2C19
SCHEMBL10889501 0.73 AOC3 (0.58) AOC3SLC2A1CYP1A2CYP2D6CYP2C19
SCHEMBL31634221 0.72 AOC3 (0.56) AOC3SLC2A1CYP1A2CYP2D6CYP2C19
SCHEMBL20079501 0.72 AOC3 (0.56) AOC3SLC2A1CYP1A2CYP2D6CYP2C19
SCHEMBL10887906 0.70 AOC3 (0.54) AOC3SLC2A1CYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1313718-A2 INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES Biotie Therapies Corp. (FI) 2003-05-28 EP claimed
WO-2002002090-A2 INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES BIOTIE THERAPIES CORP. (FI) 2002-01-10 WO claimed