SCHEMBL706673

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL708103	0.89	DRD4 (0.49)	PARP1DRD4DRD2DRD3ADRA1B
	SCHEMBL708931	0.88	KDM4E (0.50)	PARP1TNKSTNKS2PRKAA2USP14
	SCHEMBL707740	0.85	PARP1 (0.49)	PARP1TNKSTNKS2PRKAA2USP14
	SCHEMBL710453	0.82	PARP1 (0.48)	PARP1TNKSTNKS2PRKAA2USP14
	SCHEMBL710426	0.78	KDM4E (0.48)	PARP1TNKSTNKS2PRKAA2TNK1
	SCHEMBL710412	0.78	PARP1 (0.62)	PARP1TNKSTNKS2HTR7TNK1
	SCHEMBL710789	0.77	PARP1 (0.43)	PARP1TNKSTNKS2PRKAA2USP14
	SCHEMBL6128548	0.77	KDM4E (0.54)	PARP1TNKSTNKS2ADRA1DADRA1A
	SCHEMBL710432	0.77	KDM4E (0.54)	PARP1TNKSTNKS2ADRA1DADRA1A
	SCHEMBL707564	0.77	KMT2A (0.53)	PARP1TNKSTNKS2GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.