Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069257 | 0.91 | GRM2 (0.61) | GRM2ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7067345 | 0.90 | GRM2 (0.55) | GRM2 | |
| SCHEMBL7386950 | 0.89 | GRM2 (0.63) | GRM2ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7068856 | 0.89 | GRM2 (0.48) | GRM2ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7387162 | 0.88 | GRM2 (0.59) | GRM2ITGB3PRSS1ITGA2BF10 | |
| SCHEMBL7064599 | 0.87 | GRM2 (0.64) | GRM2ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7069153 | 0.87 | GRM2 (0.67) | GRM2ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7129519 | 0.86 | GRM2 (0.47) | GRM2ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7386353 | 0.86 | GRM2 (0.59) | GRM2ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7065739 | 0.86 | GRM2 (0.63) | GRM2ITGB3PRSS1PRSS2ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | claimed |
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |