Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 3/20 | 0.59 |
| ▸ | MC4R | P32245 | 2/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18556183 | 1.00 | CTSC (0.59) | CTSCMC4RDPP4HPGDUSP2 | |
| Hydrochloric Acid SCHEMBL18546507 | 0.99 | CTSC (0.58) | CTSCMC4RDPP4HPGDUSP2 | |
| Hydrochloric Acid SCHEMBL18554365 | 0.99 | CTSC (0.58) | CTSCMC4RDPP4HPGDUSP2 | |
| SCHEMBL5227415 | 0.88 | CTSC (0.47) | CTSCMC4RDPP4HPGDUSP2 | |
| SCHEMBL5227425 | 0.88 | CTSC (0.47) | CTSCMC4RDPP4HPGDUSP2 | |
| SCHEMBL18554335 | 0.87 | CTSC (0.58) | CTSCMC4RDPP4NPSR1 | |
| Hydrochloric Acid SCHEMBL18546544 | 0.86 | CTSC (0.57) | CTSCMC4RDPP4NPSR1 | |
| SCHEMBL1162854 | 0.84 | MC4R (0.59) | CTSCMC4RDPP4HPGDUSP2 | |
| SCHEMBL18554400 | 0.84 | KMT2A (0.58) | CTSCMC4RDPP4HPGDALDH1A1 | |
| SCHEMBL18554382 | 0.84 | KMT2A (0.58) | CTSCMC4RDPP4HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |