Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068020 | 0.92 | GRM2 (0.75) | GRM2KMT2AATM | |
| SCHEMBL7389228 | 0.90 | GRM2 (0.60) | GRM2 | |
| SCHEMBL7387746 | 0.85 | GRM2 (0.59) | GRM2 | |
| SCHEMBL2825673 | 0.85 | GRM2 (1.00) | GRM2KMT2AATM | |
| SCHEMBL7068146 | 0.85 | GRM2 (0.59) | GRM2 | |
| SCHEMBL7068141 | 0.85 | GRM2 (0.62) | GRM2 | |
| SCHEMBL7064486 | 0.84 | GRM2 (0.70) | GRM2 | |
| SCHEMBL7067345 | 0.84 | GRM2 (0.55) | GRM2 | |
| SCHEMBL7067364 | 0.84 | GRM2 (0.64) | GRM2 | |
| SCHEMBL7387162 | 0.83 | GRM2 (0.59) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | claimed |
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |