Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 18/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066036 | 0.89 | GRM2 (0.64) | GRM2 | |
| SCHEMBL7387746 | 0.89 | GRM2 (0.59) | GRM2 | |
| SCHEMBL7065822 | 0.88 | GRM2 (0.52) | GRM2 | |
| SCHEMBL7067648 | 0.86 | GRM2 (0.55) | GRM2 | |
| SCHEMBL7389228 | 0.85 | GRM2 (0.60) | GRM2MAOAMAOB | |
| SCHEMBL7064486 | 0.85 | GRM2 (0.70) | GRM2MAOAMAOB | |
| SCHEMBL7067364 | 0.85 | GRM2 (0.64) | GRM2MAOAMAOB | |
| SCHEMBL7064636 | 0.85 | GRM2 (0.60) | GRM2MAOAMAOB | |
| SCHEMBL7067842 | 0.84 | GRM2 (0.53) | GRM2MAOAMAOB | |
| SCHEMBL7064629 | 0.83 | GRM2 (0.64) | GRM2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | claimed |
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |