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SCHEMBL7068955

SCHEMBL7068955

CCCCC[C@H](CCCN1CCC(=O)N1CCc1ccc(C(=O)OC)cc1)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PTGER2 P43116 20/20 0.59
▸ PTGER4 P35408 19/20 0.59
▸ PTGER3 P43115 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1083324 1.00 PTGER2 (0.59) PTGER2PTGER4PTGER3
SCHEMBL1055319 1.00 PTGER2 (0.59) PTGER2PTGER4PTGER3
SCHEMBL1057878 0.97 PTGER2 (0.55) PTGER2PTGER4PTGER3
SCHEMBL1057442 0.90 PTGER2 (0.51) PTGER2PTGER4
SCHEMBL1052846 0.87 PTGER2 (0.53) PTGER2PTGER4
SCHEMBL1055275 0.86 PTGER2 (0.50) PTGER2PTGER4PTGER3
SCHEMBL1083098 0.86 PTGER2 (0.50) PTGER2PTGER4PTGER3
SCHEMBL1057563 0.85 PTGER2 (0.80) PTGER2PTGER4PTGER3
SCHEMBL1057561 0.85 PTGER2 (0.80) PTGER2PTGER4PTGER3
SCHEMBL1055565 0.85 PTGER2 (0.80) PTGER2PTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1439837-A1 PYRAZOLIDINONE COMPOUNDS AS LIGANDS OF THE PROSTAGLANDIN EP2 AND/OR EP4 RECEPTORS Applied Research Systems ARS Holding N.V. (AN) 2004-07-28 — — EP disclosed
WO-2003035064-A1 PYRAZOLIDINONE COMPOUNDS AS LIGANDS OF THE PROSTAGLANDIN EP2 AND/OR EP4 RECEPTORS APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2003-05-01 — — WO disclosed