Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 18/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131582 | 0.90 | GRM2 (0.45) | GRM2MAOAMAOB | |
| SCHEMBL7064670 | 0.90 | GRM2 (0.54) | GRM2 | |
| SCHEMBL7069831 | 0.87 | GRM2 (0.47) | GRM2MAOAMAOB | |
| SCHEMBL7067345 | 0.86 | GRM2 (0.55) | GRM2MAOAMAOB | |
| SCHEMBL7066418 | 0.86 | GRM2 (0.52) | GRM2MAOAMAOB | |
| SCHEMBL2824788 | 0.85 | GRM2 (0.70) | GRM2 | |
| SCHEMBL7389228 | 0.85 | GRM2 (0.60) | GRM2MAOAMAOB | |
| SCHEMBL7067869 | 0.85 | GRM2 (0.45) | GRM2MAOAMAOB | |
| SCHEMBL7387746 | 0.84 | GRM2 (0.59) | GRM2 | |
| SCHEMBL7064636 | 0.82 | GRM2 (0.60) | GRM2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | claimed |
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |