Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.61 |
| ▸ | F10 | P00742 | 9/20 | 0.56 |
| ▸ | PYGL | P06737 | 6/20 | 0.55 |
| ▸ | F2 | P00734 | 4/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.53 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5260262 | 0.91 | F10 (0.59) | SMYD3F10PYGLF2 | |
| SCHEMBL4360291 | 0.90 | SMYD3 (0.63) | SMYD3F10PYGLF2F7 | |
| SCHEMBL4363306 | 0.90 | SMYD3 (0.63) | SMYD3F10PYGLF2F7 | |
| SCHEMBL4360293 | 0.90 | SMYD3 (0.63) | SMYD3F10PYGLF2F7 | |
| SCHEMBL6834814 | 0.87 | MLLT1 (0.53) | SMYD3F10F2MLLT1 | |
| SCHEMBL5258969 | 0.87 | MLLT1 (0.53) | SMYD3F10F2MLLT1 | |
| SCHEMBL17149805 | 0.87 | SMYD3 (0.62) | SMYD3F10PYGLF2EHMT2 | |
| SCHEMBL12669925 | 0.86 | F10 (0.71) | SMYD3F10PYGLF2 | |
| SCHEMBL742890 | 0.86 | SMYD3 (0.67) | SMYD3F10PYGLF2EHMT2 | |
| SCHEMBL11888195 | 0.86 | SMYD3 (0.61) | SMYD3F10PYGLF2EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747053-B2 | Heteroaryl nitriles | ROCHE PALO ALTO LLC | 2004-06-08 | — | — | US | disclosed |