SCHEMBL7070822

SCHEMBL7070822

CCOC(=O)/C(F)=C/c1ccccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.49
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
LMNA P02545 5/20 0.49
PLIN1 O60240 1/20 0.49
POLB P06746 1/20 0.49
PLIN5 Q00G26 1/20 0.49
ABHD5 Q8WTS1 1/20 0.49
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
MIF P14174 1/20 0.45
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
CYP2C9 P11712 1/20 0.42
GAA P10253 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7070824 1.00 MAPT (0.49) MAPTMEN1KMT2ALMNAPLIN1
SCHEMBL4928086 0.84 MAPT (0.68) MAPTMEN1KMT2ALMNAPLIN1
SCHEMBL18069243 0.83 MAPT (0.48) MAPTMEN1KMT2ALMNAPLIN1
SCHEMBL3123681 0.83 MAPT (0.50) MAPTMEN1KMT2ALMNAPLIN1
SCHEMBL3123693 0.83 MAPT (0.50) MAPTMEN1KMT2ALMNAPLIN1
SCHEMBL4926158 0.80 MAPT (0.58) MAPTMEN1KMT2ALMNAPLIN1
SCHEMBL4926161 0.80 MAPT (0.58) MAPTMEN1KMT2ALMNAPLIN1
SCHEMBL11309469 0.79 MEN1 (0.72) MAPTMEN1KMT2ALMNAPLIN1
SCHEMBL10697747 0.79 MEN1 (0.72) MAPTMEN1KMT2ALMNAPLIN1
SCHEMBL11309467 0.79 MEN1 (0.72) MAPTMEN1KMT2ALMNAPLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0946492-B1 NOVEL 2-FLUOROACRYLIC ACID DERIVATIVES, NOVEL MIXTURES OF HERBICIDES AND ANTIDOTES AND THE USE THEREOF BAYER CROPSCIENCE GMBH (DE) 2003-06-18 EP claimed
US-5972839-A MIXTURE WITH PLANT SAFENING AGENT HOECHST SCHERING AGREVO GMBH (DE) 1999-10-26 US claimed
US-5972839-A MIXTURE WITH PLANT SAFENING AGENT HOECHST SCHERING AGREVO GMBH (DE) 1999-10-26 US disclosed