Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 7/20 | 0.43 |
| ▸ | FNTB | P49356 | 7/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071336 | 1.00 | FOLH1 (0.47) | FOLH1PTGS1GSTK1KMT2AALOX15 | |
| SCHEMBL4227222 | 0.95 | KMT2A (0.48) | FOLH1PTGS1GSTK1KMT2AALOX15 | |
| SCHEMBL4227234 | 0.95 | KMT2A (0.48) | FOLH1PTGS1GSTK1KMT2AALOX15 | |
| SCHEMBL30010559 | 0.94 | FOLH1 (0.47) | FOLH1PTGS1GSTK1KMT2AALOX15 | |
| SCHEMBL30011195 | 0.94 | FOLH1 (0.47) | FOLH1PTGS1GSTK1KMT2AALOX15 | |
| SCHEMBL6809858 | 0.94 | KMT2A (0.49) | FOLH1PTGS1GSTK1KMT2AALOX15 | |
| SCHEMBL30010917 | 0.94 | FOLH1 (0.47) | FOLH1PTGS1GSTK1KMT2AALOX15 | |
| SCHEMBL6809847 | 0.94 | KMT2A (0.49) | FOLH1PTGS1GSTK1KMT2AALOX15 | |
| SCHEMBL30010906 | 0.94 | FOLH1 (0.47) | FOLH1PTGS1GSTK1KMT2AALOX15 | |
| SCHEMBL6806102 | 0.93 | KMT2A (0.47) | FOLH1PTGS1GSTK1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055448-A2 | ANTIFUNGAL COMPOSITIONS | ACHILLION PHARMACEUTICALS, INC. (US) | 2003-07-10 | — | — | WO | disclosed |