SCHEMBL7071608

SCHEMBL7071608

CCCCC/C=C(F)/C=C/CCCCC

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.42
PPARA Q07869 2/20 0.42
EP300 Q09472 1/20 0.41
FAAH O00519 4/20 0.40
TRPV1 Q8NER1 1/20 0.40
PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7071613 1.00 PPARG (0.42) PPARGPPARAEP300FAAHTRPV1
SCHEMBL5324404 0.98 PPARG (0.44) PPARGPPARAEP300FAAHTRPV1
SCHEMBL19391258 0.88 PPARG (0.43) PPARGPPARAFAAHTRPV1PTPN1
SCHEMBL22511336 0.83 EP300 (0.41) PPARGPPARAEP300FAAHPTPN1
SCHEMBL2965815 0.76
SCHEMBL2965814 0.76
SCHEMBL10973918 0.76 PPARG (0.56) PPARGPPARAFAAHPTPN1
SCHEMBL5716968 0.76 PPARG (0.47) PPARGPPARAEP300FAAHTRPV1
SCHEMBL7071826 0.76 EP300 (0.47) PPARGPPARAEP300FAAHTRPV1
SCHEMBL10973916 0.76 PPARG (0.56) PPARGPPARAFAAHPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1202948-B1 PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AG (DE) 2003-12-10 EP claimed
US-6646166-B1 Reacting an arylmethanesulfonyl fluoride or arylmethanephos-phonate with a 3-aryl-2-fluoropropenal BASF AKTIENGESELLSCHAFT (DE) 2003-11-11 US claimed
EP-1131273-B1 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AG (DE) 2003-10-22 EP claimed
EP-1159241-B1 PROCESSES FOR THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AG (DE) 2003-08-20 EP claimed
EP-1202948-A1 PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2002-05-08 EP claimed
CN-1333742-A Process for preparation of 1,4-diaryl-2-fluoro-1,3-butadiene and 1,4-diaryl-2-fluoro-2-butene compounds BASF AG (DE) 2002-01-30 CN claimed
CN-1333741-A 1, 4-diaryl-2-fluoro-1-buten-3-ol compounds and their use in the preparation of 1, 4-diaryl-2-fluoro-1, 3-butadiene and 1, 4-diaryl-2-fluoro-2-butene compounds BASF AG (DE) 2002-01-30 CN claimed
US-6342642-B1 DEHYDROXYLATION OF HALOBUTENOL COMPOUNDS TO FORM BUTADIENES BASF AKTIENGESELLSCHAFT (DE) 2002-01-29 US claimed
EP-1159241-A1 PROCESSES FOR THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-12-05 EP claimed
US-6291721-B1 REACTING 2-ARYL ALDEHYDE COMPOUND WITH ALCOHOL OR HEATING ACETAL COMPOUND IN PRESENCE OF APROTIC SOLVENT TO PRODUCE2-ARYLVINYL ETHER COMPOUND AMERICAN CYANAMID CO. 2001-09-18 US claimed
EP-1131273-A1 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2001-09-12 EP claimed
WO-2001012578-A1 PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-02-22 WO claimed
WO-2000029362-A1 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2000-05-25 WO claimed
WO-2000029363-A1 PROCESSES FOR THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2000-05-25 WO claimed
CN-1210241-C 1,4-diaryl-2-fluoro-1-buten-3-ol compounds and their use in the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene and 1,4-diaryl-2-fluoro-2-butene compounds BASF AG (DE) 2005-07-13 CN disclosed
CN-1210241-C 1,4-diaryl-2-fluoro-1-buten-3-ol compounds and their use in the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene and 1,4-diaryl-2-fluoro-2-butene compounds BASF AG (DE) 2005-07-13 CN disclosed
CN-1210241-C 1,4-diaryl-2-fluoro-1-buten-3-ol compounds and their use in the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene and 1,4-diaryl-2-fluoro-2-butene compounds BASF AG (DE) 2005-07-13 CN disclosed
EP-1131273-A1 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2001-09-12 EP disclosed
WO-2001012578-A1 PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-02-22 WO disclosed
WO-2000029362-A1 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2000-05-25 WO disclosed