Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10530847 | 1.00 | NR1I2 (0.50) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL9482880 | 0.95 | TDP1 (0.52) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL9482885 | 0.95 | TDP1 (0.52) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL10530861 | 0.94 | NR1I2 (0.47) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL10530868 | 0.94 | NR1I2 (0.47) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL10531302 | 0.94 | NR1I2 (0.47) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL10531311 | 0.94 | NR1I2 (0.47) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL9483140 | 0.94 | NR1I2 (0.47) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL10796450 | 0.92 | MAPT (0.48) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL10796446 | 0.92 | MAPT (0.48) | NR1I2HTR2CPTGS1ABCB11PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757691-B1 | CEPHALOSPORIN SYNTHESIS | BIOCHEMIE GMBH (AT) | 2003-07-02 | — | — | EP | disclosed |
| US-6093813-A | Cephalosporin compounds | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2000-07-25 | — | — | US | disclosed |
| US-6063917-A | Cephalosporin synthesis | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2000-05-16 | — | — | US | disclosed |
| US-6034237-A | 3-imino-cephalosporins | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2000-03-07 | — | — | US | disclosed |
| EP-0103264-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |
| US-4639448-A | 7-amino-3-[substituted vinyl]-3-cephem-4-carboxylates having antimicrobial activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-01-27 | — | — | US | disclosed |
| US-4546101-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-08 | — | — | US | disclosed |
| EP-0103264-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-21 | — | — | EP | disclosed |