SCHEMBL7072974

SCHEMBL7072974

CNC(=O)C(=NOC)c1ccccc1COc1ccccc1C

nearest known ligand 0.78

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.50
ALDH1A1 P00352 1/20 0.43
CYP1A2 P05177 1/20 0.43
SGMS2 Q8NHU3 1/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
TP53 P04637 1/20 0.40
HTT P42858 1/20 0.40
RECQL P46063 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8368495 1.00 HIF1A (0.50) HIF1AALDH1A1CYP1A2SGMS2MAPT
SCHEMBL7221376 1.00 HIF1A (0.50) HIF1AALDH1A1CYP1A2SGMS2MAPT
SCHEMBL8369928 0.92 HIF1A (0.50) HIF1AALDH1A1SGMS2MAPTTDP1
SCHEMBL8369929 0.92 HIF1A (0.50) HIF1AALDH1A1SGMS2MAPTTDP1
SCHEMBL8398840 0.92 HIF1A (0.50) HIF1AALDH1A1SGMS2MAPTTDP1
SCHEMBL7969954 0.91 HIF1A (0.50) HIF1AALDH1A1SGMS2MAPTTDP1
SCHEMBL8883792 0.89 HIF1A (0.49) HIF1ASGMS2MAPTTDP1RXRA
SCHEMBL9015765 0.89 HIF1A (0.49) HIF1ASGMS2MAPTTDP1RXRA
SCHEMBL8624133 0.89 HIF1A (0.57) HIF1AALDH1A1MAPTRXRATP53
SCHEMBL8624136 0.89 HIF1A (0.57) HIF1AALDH1A1MAPTRXRATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5516804-A FUNGICIDES FOR PLANTS BASF AKTIENGESELLSCHAFT (DE) 1996-05-14 US claimed
US-5395854-A Fungicides BASF AKTIENGESELLSCHAFT (DE) 1995-03-07 US claimed
US-6605631-B1 Controlling fungi and pests; improved activity and plant tolerability BASF AKTIENGESELLSCHAFT (DE) 2003-08-12 US disclosed
EP-1105372-B1 METHOXIMINOPHENYLACETIC ACID AMIDES BAYER CROPSCIENCE AG (DE) 2003-06-11 EP disclosed
US-6403600-B1 FUNGICIDES. BAYER AKTIENGESELLSCHAFT (DE) 2002-06-11 US disclosed
US-6310071-B1 FUNGICIDES, INSECTICIDES, MITICIDES, NEMATOCIDES BASF AKTIENGESELLSCHAFT (DE) 2001-10-30 US disclosed
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO disclosed
EP-1105372-A1 METHOXIMINOPHENYLACETIC ACID AMIDES BAYER AG (DE) 2001-06-13 EP disclosed
US-6114342-A 2-(O-[pyrimidin-4-yl]methylenoxy)phenylacetic acid derivatives and their use for controlling harmful fungi and animal pests BASF AKTIENGESELLSCHAFT (DE) 2000-09-05 US disclosed
WO-2000010970-A1 METHOXIMINOPHENYLACETIC ACID AMIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-03-02 WO disclosed
US-6031110-A Ortho-substituted 2-methoxyiminophenyl-N-methylacetamides BASF AKTIENGESELLSCHAFT (DE) 2000-02-29 US disclosed
US-5510506-A Process for producing carboxylic acid derivatives SHIONOGI & CO., LTD. (JP) 1996-04-23 US disclosed
US-5506358-A USEFUL AS AGRICULTURAL FUNGICIDES SHIONOGI & CO., LTD. (JP) 1996-04-09 US disclosed
US-5506254-A INSECTICIDE, PESTICIDE, MITICIDES, NEMATOCIDES BASF AKTIENGESELLSCHAFT (DE) 1996-04-09 US disclosed
US-5498792-A Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1996-03-12 US disclosed
EP-0658541-A1 PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE SHIONOGI & CO., LTD. (JP) 1995-06-21 EP disclosed
EP-0644183-A2 Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1995-03-22 EP disclosed
US-5395854-A Fungicides BASF AKTIENGESELLSCHAFT (DE) 1995-03-07 US disclosed
US-5393782-A Fungicides BASF AKTIENGESELLSCHAFT (DE) 1995-02-28 US disclosed
EP-0617011-A2 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO., LTD. (JP) 1994-09-28 EP disclosed