Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499901 | 0.88 | ABL1 (0.54) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14609800 | 0.83 | MAPT (0.54) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5500307 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRCASP1KDM4EALDH1A1 | |
| SCHEMBL3136286 | 0.81 | MEN1 (0.50) | MAPTSMN1; SMN2CASP1MEN1KMT2A | |
| SCHEMBL15071460 | 0.81 | MAPT (0.49) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4608717 | 0.80 | MAPT (0.48) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4609201 | 0.80 | MAPT (0.48) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11532393 | 0.80 | MAPT (0.57) | MAPTALDH1A1EGFR | |
| SCHEMBL6057229 | 0.79 | FLT1 (0.57) | SMN1; SMN2TSHRCASP1KDM4EALDH1A1 | |
| SCHEMBL5458601 | 0.79 | ABL1 (0.54) | KDM4EALDH1A1ABL1NPSR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105367-B1 | SUBSTITUTED CINNAMIC ACIDS AND CINNAMIC ACID ESTERS | BAYER AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-6455725-B1 | Substituted cinnamic acids and cinnamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | disclosed |
| EP-1105367-A1 | SUBSTITUTED CINNAMIC ACIDS AND CINNAMIC ACID ESTERS | Bayer Aktiengesellschaft (DE) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010963-A1 | SUBSTITUTED CINNAMIC ACIDS AND CINNAMIC ACID ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-02 | — | — | WO | disclosed |