Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314583 | 1.00 | GLA (0.37) | GLAEGFRNR1I2HMGCRMAPT | |
| SCHEMBL6306416 | 1.00 | GLA (0.37) | GLAEGFRNR1I2HMGCRMAPT | |
| SCHEMBL6309125 | 0.94 | GLA (0.39) | GLANR1I2HMGCRMAPTMEN1 | |
| SCHEMBL6309422 | 0.94 | GLA (0.39) | GLANR1I2HMGCRMAPTMEN1 | |
| SCHEMBL7078673 | 0.94 | GLA (0.39) | GLANR1I2HMGCRMAPTMEN1 | |
| SCHEMBL6307628 | 0.86 | EGFR (0.37) | GLAEGFRMAPTMEN1KMT2A | |
| SCHEMBL6307626 | 0.86 | EGFR (0.37) | GLAEGFRMAPTMEN1KMT2A | |
| SCHEMBL6305958 | 0.84 | TSHR (0.41) | EGFRMAPTMEN1KMT2APOLB | |
| SCHEMBL6314533 | 0.84 | SMN1; SMN2 (0.42) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL6307314 | 0.84 | TSHR (0.41) | EGFRMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320536-A1 | $g(a)-SUBSTITUTED $g(b)-AMINOETHYL PHOSPHONATES | Ilex Oncology Research S.A. (CH) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002026752-A1 | α-SUBSTITUTED β-AMINOETHYL PHOSPHONATES | ILEX ONCOLOGY RESEARCH S.A. (CH) | 2002-04-04 | — | — | WO | disclosed |