Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128475 | 0.83 | TSHR (0.31) | TSHR | |
| SCHEMBL17074742 | 0.79 | MEN1 (0.33) | — | |
| SCHEMBL15058118 | 0.77 | — | — | |
| SCHEMBL24021664 | 0.76 | TSHR (0.32) | TSHR | |
| SCHEMBL13195788 | 0.76 | — | — | |
| SCHEMBL7160076 | 0.75 | TSHR (0.42) | TSHR | |
| SCHEMBL6932478 | 0.74 | TSHR (0.41) | TSHR | |
| SCHEMBL3454200 | 0.73 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL319242 | 0.72 | — | — | |
| SCHEMBL21876779 | 0.71 | MEN1 (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339686-A2 | CYANOGUANIDINE PRODRUGS | Leo Pharma A/S (DK) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002042265-A2 | CYANOGUANIDINE PRODRUGS | LEO PHARMA A/S (DK) | 2002-05-30 | — | — | WO | disclosed |