Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070791 | 0.75 | ESR2 (0.38) | ESR1ESR2 | |
| SCHEMBL6796544 | 0.71 | ESR1 (0.57) | ESR1ESR2HRH3 | |
| SCHEMBL6801025 | 0.66 | HRH3 (0.57) | ESR1ESR2HRH3 | |
| SCHEMBL6797161 | 0.64 | ESR1 (0.58) | ESR1ESR2HRH3 | |
| SCHEMBL5578990 | 0.60 | ESR1 (0.61) | ESR1ESR2 | |
| SCHEMBL6829259 | 0.60 | ESR1 (0.51) | ESR1ESR2HRH3 | |
| SCHEMBL6796784 | 0.59 | HRH3 (0.57) | ESR1HRH3 | |
| SCHEMBL1796383 | 0.59 | HRH3 (0.72) | HRH3 | |
| SCHEMBL1797535 | 0.59 | HRH3 (0.72) | HRH3 | |
| SCHEMBL11754397 | 0.59 | HRH3 (0.72) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339662-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046134-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2002-06-13 | — | — | WO | disclosed |