Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.56 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.56 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.55 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075684 | 1.00 | P2RY12 (0.58) | P2RY12P2RY2P2RY1P2RY6DNPH1 | |
| SCHEMBL7065329 | 0.90 | P2RY12 (0.48) | P2RY12P2RY2P2RY1P2RY6DNPH1 | |
| SCHEMBL7065332 | 0.90 | P2RY12 (0.48) | P2RY12P2RY2P2RY1P2RY6DNPH1 | |
| SCHEMBL5511440 | 0.89 | P2RY12 (0.47) | P2RY12P2RY2P2RY1P2RY6DNPH1 | |
| SCHEMBL7251211 | 0.89 | P2RY12 (0.47) | P2RY12P2RY2P2RY1P2RY6DNPH1 | |
| SCHEMBL7251669 | 0.89 | P2RY12 (0.47) | P2RY12P2RY2P2RY1P2RY6DNPH1 | |
| SCHEMBL5507463 | 0.89 | P2RY12 (0.47) | P2RY12P2RY2P2RY1P2RY6DNPH1 | |
| SCHEMBL7063487 | 0.89 | P2RY12 (0.47) | P2RY12P2RY2P2RY1P2RY6DNPH1 | |
| SCHEMBL7063482 | 0.89 | P2RY12 (0.47) | P2RY12P2RY2P2RY1P2RY6DNPH1 | |
| SCHEMBL5507017 | 0.88 | P2RY12 (0.46) | P2RY12P2RY2P2RY1P2RY6DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059926-A2 | METHODS AND COMPOSITIONS FOR AMINOACYL-tRNA SYNTHESIS | UNIVERSITY OF MASSACHUSETTS (US) | 2003-07-24 | — | — | WO | disclosed |