SCHEMBL7075784

SCHEMBL7075784

C/C=C/CP(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAOB P27338 1/20 0.32
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7075788 1.00 CYP3A4 (0.36) CYP3A4TDP1MAOBESR1ESR2
SCHEMBL15759942 1.00 CYP3A4 (0.36) CYP3A4TDP1MAOBESR1ESR2
SCHEMBL4972429 0.85 CYP3A4 (0.43) CYP3A4TDP1MAOBESR1ESR2
SCHEMBL8104110 0.81 CYP3A4 (0.39) CYP3A4TDP1ESR1ESR2
SCHEMBL7922209 0.77 CYP3A4 (0.36) CYP3A4TDP1MAOB
SCHEMBL6408532 0.76 CYP3A4 (0.35) CYP3A4TDP1MAOB
SCHEMBL16240152 0.76 IDO1 (0.45) TDP1MAOB
SCHEMBL16240154 0.76 IDO1 (0.45) TDP1MAOB
SCHEMBL4974727 0.76 CYP3A4 (0.35) CYP3A4TDP1MAOB
SCHEMBL4974734 0.76 CYP3A4 (0.35) CYP3A4TDP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1332124-A1 PROCESS FOR THE CARBONYLATION OF A CONJUGATED DIENE DSM N.V. (NL) 2003-08-06 EP disclosed
WO-2002026690-A1 PROCESS FOR THE CARBONYLATION OF A CONJUGATED DIENE DSM N.V. (NL) 2002-04-04 WO disclosed