SCHEMBL7076579

SCHEMBL7076579

CC(=COc1ccc(Cl)c(C)c1Cl)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
AKR1C3 P42330 2/20 0.33
CCR3 P51677 3/20 0.32
HRH1 P35367 1/20 0.32
KCNH2 Q12809 1/20 0.32
APEX1 P27695 2/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
MT-CO2 P00403 1/20 0.31
LMNA P02545 1/20 0.31
TTR P02766 1/20 0.31
PLA2G1B P04054 1/20 0.31
CYP1A2 P05177 1/20 0.31
PGR P06401 1/20 0.31
CYP3A4 P08684 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
ADORA3 P0DMS8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7072248 0.72 AKR1C3 (0.43) AKR1C3APEX1TDP1MEN1KMT2A
SCHEMBL7071848 0.72 CYP3A4 (0.37) KDM4EAKR1C3APEX1TSHRLMNA
SCHEMBL2811159 0.70 AKR1C3 (0.44) KDM4EAKR1C3APEX1TSHRTDP1
SCHEMBL2811157 0.70 AKR1C3 (0.44) KDM4EAKR1C3APEX1TSHRTDP1
SCHEMBL7076716 0.70 KMT2A (0.44) KDM4EAKR1C3APEX1TSHRLMNA
SCHEMBL2811418 0.68 MEN1 (0.44) KDM4EAKR1C3TSHRTDP1MEN1
SCHEMBL2811414 0.68 MEN1 (0.44) KDM4EAKR1C3TSHRTDP1MEN1
SCHEMBL10615826 0.68 TSHR (0.58) KDM4ETSHRTDP1CYP1A2CYP2C9
SCHEMBL14006497 0.68 TSHR (0.43) KDM4ETSHRMEN1LMNACYP1A2
SCHEMBL7079311 0.68 MAPK1 (0.46) TSHRTDP1MEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030096172-A1 Hologram recording material composition and hologram recording medium DAISO CO., LTD. (JP) 2003-05-22 US disclosed