SCHEMBL7076965

SCHEMBL7076965

N#Cc1cc(F)cc(Oc2cccc(Oc3cc(C#N)cc(C#N)c3)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.52
FFAR4 Q5NUL3 1/20 0.52
EPAS1 Q99814 11/20 0.47
HAO1 Q9UJM8 1/20 0.45
VEGFA P15692 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7071576 0.93 FFAR1 (0.49) FFAR1FFAR4EPAS1HAO1VEGFA
SCHEMBL7071539 0.93 FFAR1 (0.49) FFAR1FFAR4EPAS1HAO1VEGFA
SCHEMBL7070749 0.89 SMN1; SMN2 (0.50) FFAR1FFAR4EPAS1
SCHEMBL7074972 0.87 EPAS1 (0.44) FFAR1FFAR4EPAS1VEGFA
SCHEMBL7072557 0.85 PDE4A (0.50) FFAR1FFAR4EPAS1VEGFA
SCHEMBL7069974 0.85 PDE4A (0.50) FFAR1FFAR4EPAS1VEGFA
SCHEMBL921798 0.84 FFAR1 (0.50) FFAR1FFAR4EPAS1HAO1VEGFA
SCHEMBL7070717 0.83 MEN1 (0.50) FFAR1FFAR4
SCHEMBL7073983 0.81 CYP19A1 (0.54) FFAR1FFAR4
SCHEMBL27839327 0.81 PDE4A (0.53) FFAR1FFAR4EPAS1VEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030181334-A1 Herbicidal method BAYER CROPSCIENCE LIMITED (GB) 2003-09-25 US disclosed
WO-2003051119-A1 NEW HERBICIDAL COMPOUNDS AND METHOD BAYER CROPSCIENCE LIMITED (GB) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030181334-A1 Herbicidal method DDT, HAAO, CYP4X1 FFAR1 3072/4885FFAR4 3402/4885EPAS1 4199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.