Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934980 | 0.82 | STAT3 (0.43) | CYP2D6STAT3KMT2ASMN1; SMN2VDR | |
| SCHEMBL16641783 | 0.70 | KMT2A (0.49) | CYP2D6STAT3CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL30609565 | 0.69 | KMT2A (0.49) | CYP2D6STAT3KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15286533 | 0.69 | KMT2A (0.45) | CYP2D6STAT3KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7949968 | 0.69 | CYP2D6 (0.41) | CYP2D6STAT3CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL20569464 | 0.68 | SMN1; SMN2 (0.39) | CYP2D6STAT3CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL17316452 | 0.68 | KMT2A (0.40) | CYP2D6STAT3CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL20898576 | 0.68 | STAT3 (0.41) | CYP2D6STAT3KMT2ASMN1; SMN2VDR | |
| SCHEMBL18047923 | 0.68 | SMN1; SMN2 (0.46) | CYP2D6STAT3CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL31585412 | 0.67 | STAT3 (0.40) | CYP2D6STAT3CYP1A2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |