SCHEMBL7077280

SCHEMBL7077280

N#Cc1cc(C#N)cc(Oc2cccc(Oc3ccc(C#N)c(C(F)(F)F)c3)c2)c1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 20/20 0.71
PGR P06401 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8544583 0.93 AR (0.81) ARPGR
SCHEMBL7074662 0.89 AR (0.56) AR
SCHEMBL22353402 0.85 AR (0.75) AR
SCHEMBL4188866 0.83 AR (0.71) AR
SCHEMBL4171092 0.82 AR (0.74) AR
SCHEMBL7069917 0.82 CYP19A1 (0.58) AR
SCHEMBL7070347 0.81 AR (0.48) AR
SCHEMBL7076982 0.80 AR (0.46) AR
SCHEMBL7070749 0.79 SMN1; SMN2 (0.50) ARPGR
SCHEMBL7071618 0.79 POLB (0.44) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030181334-A1 Herbicidal method BAYER CROPSCIENCE LIMITED (GB) 2003-09-25 US disclosed
WO-2003051119-A1 NEW HERBICIDAL COMPOUNDS AND METHOD BAYER CROPSCIENCE LIMITED (GB) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030181334-A1 Herbicidal method DDT, HAAO, CYP4X1 AR 4356/4885PGR 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.