SCHEMBL707754

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL709347	0.83	LPAR1 (0.78)	LPAR1LMNASMN1; SMN2HTTTDP1
	SCHEMBL707807	0.82	LPAR1 (0.59)	LPAR1LMNASMN1; SMN2HTTTDP1
	SCHEMBL7721920	0.78	TP53 (0.57)	LPAR1LMNASMN1; SMN2HTTTDP1
	SCHEMBL19438511	0.77	LPAR1 (0.62)	LPAR1LMNASMN1; SMN2HTTTDP1
	SCHEMBL709246	0.76	TDP1 (0.60)	LPAR1LMNASMN1; SMN2HTTTDP1
	SCHEMBL708221	0.76	LPAR1 (0.76)	LPAR1LPAR2
	SCHEMBL13580891	0.75	HSP90AA1 (0.48)	TDP1
	SCHEMBL708091	0.75	LPAR1 (0.69)	LPAR1LPAR2
	SCHEMBL714380	0.75	LPAR1 (0.72)	LPAR1LPAR2
	SCHEMBL708598	0.75	LPAR1 (0.84)	LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.