Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19364501 | 1.00 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM3ALKBH5 | |
| SCHEMBL16766368 | 1.00 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM3ALKBH5 | |
| SCHEMBL719296 | 1.00 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM3ALKBH5 | |
| SCHEMBL29691892 | 1.00 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM3ALKBH5 | |
| Hydrochloric Acid SCHEMBL1633577 | 0.98 | CHRM2 (0.56) | CHRM2CHRM4CHRM5CHRM3ALKBH5 | |
| SCHEMBL12902953 | 0.93 | KMT2A (0.51) | CHRM2CHRM4CHRM5CHRM3SIGMAR1 | |
| SCHEMBL15425873 | 0.93 | KMT2A (0.51) | CHRM2CHRM4CHRM5CHRM3SIGMAR1 | |
| SCHEMBL911191 | 0.93 | KMT2A (0.51) | CHRM2CHRM4CHRM5CHRM3SIGMAR1 | |
| SCHEMBL6153627 | 0.92 | CHRM2 (0.56) | CHRM2CHRM4CHRM5CHRM3ALKBH5 | |
| Hydrochloric Acid SCHEMBL18063 | 0.91 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 765 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812529-B | Preparation method of N-benzyl tropine | 北京世纪迈劲生物科技有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118812529-A | Preparation method of N-benzyl tropine | 北京世纪迈劲生物科技有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-116751196-A | Method for efficiently synthesizing maraviroc intermediate N-benzyl tropylamine | 大连万福制药有限公司 | 2023-09-15 | — | — | CN | claimed |
| EP-4692084-A1 | NOVEL DERIVATIVES OF N-SUBSTITUTED NORTROPINONE, THEIR PRODUCTION AND THEIR USE | Siegfried AG (CH) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025110815-A1 | IMIDAZO [1,2-B] PYRIDAZINE-BASED NOVEL COMPOUND AS CDK INHIBITOR AND USE THEREOF | 아이리드비엠에스 주식회사 | 2025-05-30 | — | — | WO | disclosed |
| CN-112513050-B | Heterocyclic compounds which inhibit SHP2 activity | 大鹏药品工业株式会社 | 2024-12-20 | — | — | CN | disclosed |
| CN-118812529-B | Preparation method of N-benzyl tropine | 北京世纪迈劲生物科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118812529-B | Preparation method of N-benzyl tropine | 北京世纪迈劲生物科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118812529-A | Preparation method of N-benzyl tropine | 北京世纪迈劲生物科技有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118812529-A | Preparation method of N-benzyl tropine | 北京世纪迈劲生物科技有限公司 | 2024-10-22 | — | — | CN | disclosed |
| US-12037345-B2 | Heterobicyclic compounds for inhibiting the activity of SHP2 | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-16 | — | — | US | disclosed |
| EP-0013138-B1 | AZABICYCLOALKYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-12-07 | — | — | EP | disclosed |
| US-4411902-A | ANTISPASMODICS | VALEAS S.P.A. (IT) | 1983-10-25 | — | — | US | disclosed |
| EP-0081054-A2 | Azabicyclo alkyl derivatives | BEECHAM GROUP PLC (GB) | 1983-06-15 | — | — | EP | disclosed |
| US-4366154-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | SANDOZ, INC. (US) | 1982-12-28 | — | — | US | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| US-4336259-A | DOPAMINE ANTAGONIST, NERVOUS SYSTEM DISORDERS AND GASTROINTESTINAL DISORDERS | BEECHAM GROUP LIMITED (GB) | 1982-06-22 | — | — | US | disclosed |
| EP-0042365-A1 | Salts of endo-8-methyl-8-syn-alkyl-8-azoniabicyclo-(3.2.1)-octane-3-alkylcarboxylates, process for their preparation and therapeutic compositions containing them | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1981-12-23 | — | — | EP | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |
| US-4273778-A | TREATMENT OF GASTROINTESTINAL DISORDERS, NERVOUS SYSTEM DISORDERS, AND PSYCHOLOGICAL DISORDERS | BEECHAM GROUP, LIMITED (GB) | 1981-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037345-B2 | Heterobicyclic compounds for inhibiting the activity of SHP2 | PTPN1, PTPN9, PTPN7 | CHRM2 2188/4885CHRM4 2166/4885CHRM5 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.