Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078889 | 1.00 | SLC18A3 (0.41) | SLC18A3NAAANLRP3GRM2CYP2D6 | |
| SCHEMBL7078891 | 1.00 | SLC18A3 (0.41) | SLC18A3NAAANLRP3GRM2CYP2D6 | |
| SCHEMBL3058480 | 0.78 | SLC18A3 (0.40) | SLC18A3NAAA | |
| SCHEMBL3058476 | 0.78 | SLC18A3 (0.40) | SLC18A3NAAA | |
| SCHEMBL3058478 | 0.78 | SLC18A3 (0.40) | SLC18A3NAAA | |
| SCHEMBL8109803 | 0.78 | DPP4 (0.38) | NAAAGRM2DGAT1 | |
| Hydrochloric Acid SCHEMBL3058456 | 0.77 | SLC18A3 (0.40) | SLC18A3NAAA | |
| Hydrochloric Acid SCHEMBL3058459 | 0.77 | SLC18A3 (0.40) | SLC18A3NAAA | |
| Hydrochloric Acid SCHEMBL20959320 | 0.76 | DPP4 (0.38) | NAAAGRM2DGAT1 | |
| SCHEMBL14377510 | 0.76 | SLC18A3 (0.49) | SLC18A3CYP2D6CYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| US-6350774-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2002-02-26 | — | — | US | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |