Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10223189 | 0.84 | HRH1 (0.44) | HRH1KLKB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL21419245 | 0.82 | HRH1 (0.43) | HRH1KLKB1ALDH1A1PKM | |
| SCHEMBL6676408 | 0.81 | HRH1 (0.42) | HRH1KLKB1SMN1; SMN2PKM | |
| SCHEMBL12667263 | 0.79 | HRH1 (0.41) | HRH1 | |
| SCHEMBL11926965 | 0.78 | HRH1 (0.45) | HRH1KLKB1 | |
| SCHEMBL3760695 | 0.76 | HRH1 (0.44) | HRH1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL442074 | 0.76 | HRH1 (0.44) | HRH1KLKB1 | |
| SCHEMBL12926881 | 0.76 | HRH1 (0.44) | HRH1KLKB1 | |
| SCHEMBL5524100 | 0.74 | HSD17B10 (0.56) | HRH1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1107385 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |