Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 12/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079819 | 0.86 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL7080464 | 0.85 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL7078958 | 0.83 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL7078957 | 0.83 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL5173645 | 0.80 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7568658 | 0.78 | MAPK14 (0.43) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL7079665 | 0.78 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL7079667 | 0.78 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL7083138 | 0.77 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11PTK6 | |
| SCHEMBL7083133 | 0.77 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-04-17 | — | — | US | claimed |
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-04-17 | — | — | US | disclosed |
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | MAPKAPK2, MAP3K2, MAP3K1 | MAPK14 28/4885MAPK13 33/4885MAPK12 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.