SCHEMBL7080231

SCHEMBL7080231

C=CCCCC(CC)=C(CCC=C)CCC(=C)C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.31
ABCC4 O15439 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8072586 0.80 TSHR (0.50) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL139284 0.77
SCHEMBL8075948 0.77 TSHR (0.43) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL11758972 0.75
SCHEMBL8206027 0.75 TSHR (0.35) TSHRALDH1A1
SCHEMBL8072649 0.74 TSHR (0.44) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL8072647 0.74 TSHR (0.44) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL8075873 0.73 TSHR (0.46) TSHRALDH1A1
SCHEMBL8075874 0.73 TSHR (0.46) TSHRALDH1A1
SCHEMBL11103689 0.73 TSHR (0.33) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0924182-B1 Process for the preparation of aldehydes CELANESE CHEM EUROPE GMBH (DE) 2003-07-02 EP disclosed
EP-1019354-B1 METHOD FOR PRODUCING ALDEHYDES CELANESE CHEM EUROPE GMBH (DE) 2001-12-05 EP disclosed
EP-1019354-A1 METHOD FOR PRODUCING ALDEHYDES Celanese Chemicals Europe GmbH (DE) 2000-07-19 EP disclosed
EP-0924182-A1 Process for the preparation of aldehydes Celanese GmbH (DE) 1999-06-23 EP disclosed
WO-1999016737-A1 METHOD FOR PRODUCING ALDEHYDES CELANESE CHEMICALS EUROPE GMBH (DE) 1999-04-08 WO disclosed
EP-0719753-B1 Process for the preparation of aldehydes CELANESE GMBH (DE) 1999-04-07 EP disclosed
EP-0571819-B1 Sulfonated 2,2'-bis(diphenylphosphinomethyl)-1,1'-binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinic unsaturated compounds CELANESE GMBH (DE) 1998-11-11 EP disclosed
EP-0575785-B1 3,4-dimethyl-2,5,6-tris/p-sulfonatophenyl)-1-phosphanorbornadiene, process for its preparation and process for hydroformulation of olefinic unsaturated compounds HOECHST AG (DE) 1997-01-08 EP disclosed
US-5565398-A Sulfonated 2,2'-bis (Diphenylphosphinomethyl)-1,1'-binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinically unsaturated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-10-15 US disclosed
EP-0719753-A1 Process for the preparation of aldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-03 EP disclosed
US-5481045-A Sulfonated 2,2'-bis (diphenylphosphinomethyl)-1,1'-binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinically unsaturated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-02 US disclosed
EP-0491239-B1 Process for the preparation of aldehydes HOECHST AG (DE) 1995-04-26 EP disclosed
US-5347045-A Sulfonated 2,2'-bis (diphenylphosphinomethyl)-1,1'-binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinically unsaturated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-13 US disclosed
US-5312951-A 3,4-dimethyl-2,5,6-tris(p-sulfonatophenyl)-1-phosphanorbornadiene, process for the preparation thereof and process for the hydroformylation of olefinnically unsaturated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1994-05-17 US disclosed
EP-0575785-A1 3,4-dimethyl-2,5,6-tris/p-sulfonatophenyl)-1-phosphanorbornadiene, process for its preparation and process for hydroformulation of olefinic unsaturated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-29 EP disclosed
EP-0571819-A1 Sulfonated 2,2'-bis(diphenylphosphinomethyl)-1,1'binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinic unsaturated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-01 EP disclosed
US-5223648-A Hydroformylation of olefins; using water soluble rhodium complex catalyst HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-29 US disclosed
US-5200380-A Catalyst containing rhodium and sulfonated diphosphine HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-06 US disclosed
EP-0491239-A2 Process for the preparation of aldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-24 EP disclosed