SCHEMBL7080241

SCHEMBL7080241

CC1CCCN(c2ccc(C(=O)Nc3cc(C(=O)O)ccc3C(=O)Nc3ccc(Cl)cn3)cn2)CN1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 18/20 0.47
KCNH2 Q12809 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7075564 0.90 F10 (0.58) F10KCNH2
SCHEMBL6947931 0.86 F10 (0.51) F10KCNH2
SCHEMBL7080109 0.86 F10 (0.53) F10KCNH2
SCHEMBL5206177 0.85 F10 (0.64) F10
SCHEMBL5202321 0.84 F10 (0.59) F10KCNH2
SCHEMBL7076896 0.81 F10 (0.49) F10KCNH2
SCHEMBL7075919 0.79 F10 (0.51) F10KCNH2
SCHEMBL7073958 0.78 F10 (0.49) F10KCNH2
SCHEMBL6953757 0.77 F10 (0.48) F10KCNH2
SCHEMBL5202404 0.77 F10 (0.57) F10KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1307444-A2 SUBSTITUTED HETEROCYCLIC AMIDES ELI LILLY AND COMPANY (US) 2003-05-07 EP disclosed
WO-2002010154-A2 SUBSTITUTED HETEROCYCLIC AMIDES ELI LILLY AND COMPANY (US) 2002-02-07 WO disclosed